Journal: Scientific Reports
Article Title: Diversity and antimicrobial resistance profiles of Mycobacterium avium complex clinical isolates in Thailand based on whole genome comparative analysis
doi: 10.1038/s41598-024-84511-z
Figure Lengend Snippet: SNP-based phylogenetic tree of Mycobacterium intracellulare / Mycobacterium paraintracellulare isolates in Thailand. The phylogenetic tree based on SNPs from the Snippy pipeline showed the diversity of M. intracellulare / M. paraintracellulare isolates in Thailand and their phylogenetic relationships compared to global reference strains. The tree presented three clades, including M. intracellulare subsp. intracellulare group (MI; blue), M. intracellulare subsp. chimaera group (MC; red), and unknown clade. Drug susceptibility, specimen types, and origins are presented as a color strip labelled beside the tips of the tree.
Article Snippet: These isolates were identified to species or complex level based on LPA kits using the GenoType Mycobacterium CM VER 2.0 (Hain Lifescience) ( M. avium and M. intracellulare ), GenoType NTM-DR assay (Hain Lifescience) ( M. avium , M. intracellulare , and M. chimaera ), or INNO-LiPA MYCOBACTERIA v2 (Fujirebio) ( M. avium and M. intracellulare ) following the manufacturer’s protocol.
Techniques: Stripping Membranes